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课题组近年来主要针对水飞蓟宾等具有抗肿瘤作用的天然药物开展药理研究工作,并探讨胶原、明胶等细胞外基质在药物发挥药效过程中对炎症反应和细胞衰老等现象的调节作用,以及肠道微生物在药物的刺激下对机体相关功能的调控研究。此外,该课题组还围绕与衰老或细胞死亡(凋亡、自噬、坏死)有关的皮肤炎症、糖尿病及神经退行性病(阿尔茨海默病)等开展研究工作,为新型的具有抗炎、抗衰老以及抗癌作用的药物开发工作奠定相应的药理依据。

课题组池岛乔教授积极组织课题组内科研活动,有效地向研究生们介绍最新、最前沿的科学研究,为学校培养优秀博士和硕士研究生,为社会输送优秀人才,以及为优秀人才的出国留学等奠定了相应的科研基础。池岛乔教授在沈阳药科大学工作的期间内已培养博士毕业生40人,硕士毕业生49人,目前指导研究生22名(博士7名、硕士15名)和多名专题生,已发表论文250余篇其中SCI论文190余篇。

The research group mainly focuses on pharmacological investigations of anti-cancerherbal medicines such as silibinin, and evaluates the effects of extracellularmatrix and microorganisms on inflammation and cell aging with theadministration of medicines. In addition, as the diseases associated withsenescence and cell death (apoptosis, autophagy and necrosis), skininflammation, diabetes and neurodegenerative diseases such as Alzheimer’sdisease are further investigated to uncover potential targets for thedevelopment of anti-inflammatory, anti-aging and anti-cancer drugs.


Takashi Ikejima, the principle investigator of the research group, has beenworking on organizing a variety of the scientific research activities tointroduce the cutting-edge scientific discoveries to students. During theperiod working in Shenyang Pharmaceutical University, professor Ikejima haspublished more than 250 papers including more than 190 SCI papers, and 89postgraduate students including 40 Ph.D. and 49 master students were graduatedunder the supervision of professor Ikejima, in addition, 7 Ph.D. and 15 masterstudents are working in the research group currently.


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